Letter to the Editor: Genetic Editing of Secretory Pathway of Penicillium Chrysogenum After Observation of Increased Secretory Rates in an Increased Stress Environment (Microgravity), a Research Proposal by High School Students in Dubai

  • Akio Shirali The Cranleigh School
  • Wilson Minter Huijsmans The Cranleigh School
  • Matteo Sottocornola The Cranleigh School
Keywords: Penicillium Chrysogenum, CRISPR cas-9, miniPCR, RTQ-PCR, microgravity, beta-lactam antibiotics

Abstract

In this study, we aim to amplify the secretory pathway of Penicillium Chrysogenum within the ISS or similar simulated microgravity using the miniPCR and/or RTQ-PCR and then optimizing Penicillium Chrysogenum function using CRISPR cas-9 (Clustered Regularly Interspaced Short Palindromic Repeats), a new technology in the genetics which can help in gene alteration for better drug production. The secretory pathway of Penicillium Chrysogenum is controlled by genes pcbAB , pcbC and penDE
Published
2018-12-21
How to Cite
Shirali, A., Huijsmans, W., & Sottocornola, M. (2018). Letter to the Editor: Genetic Editing of Secretory Pathway of Penicillium Chrysogenum After Observation of Increased Secretory Rates in an Increased Stress Environment (Microgravity), a Research Proposal by High School Students in Dubai. Fine Focus, 4(2), 163-169. Retrieved from https://openjournals.bsu.edu/finefocus/article/view/1547