How CRISPR-Mediated Genome Editing is Affecting Undergraduate Biology Education

  • Ethan S. Pickerill Ball State University
  • Caleb M. Embree The Ohio State University
  • Ben A. Evans Ball State University
  • Elena R. North Ball State University
  • Gennifer M. Mager Ball State University
  • Douglas A. Bernstein Ball State University
Keywords: Clustered Regularly Interspaced Short Palindromatic Repeats, CRISPR, genome editing, biology education, Course-Based Undergraduate Research Experiences, CURES

Abstract

In 2010, the CRISPR/Cas system of Streptococcus thermophilus was found necessary and sufficient to cleave bacteriophage DNA. Since this time, CRISPR went from a niche scientific field to the laboratories of major research institutions, undergraduate classrooms, and popular culture. In the future, CRISPR may stand along with PCR, DNA sequencing, and transformation as paradigm shifting discoveries in molecular biology. CRISPR genome editing is technically uncomplicated and relatively inexpensive. Thus, CRISPR-mediated genome editing has been adopted by and applied to undergraduate curricula in a wide variety of ways. In this review, we provide an overview of CRISPR-mediated genome editing and examine some of the ways this technology is being leveraged to train students in the classroom and laboratory.

Published
2019-10-16
How to Cite
Pickerill, E., Embree, C., Evans, B., North, E., Mager, G., & Bernstein, D. (2019). How CRISPR-Mediated Genome Editing is Affecting Undergraduate Biology Education. Fine Focus, 5(1), 23-34. Retrieved from https://openjournals.bsu.edu/finefocus/article/view/2081
Section
Articles